Review



tlr7 8 agonist cl 075  (InvivoGen)


Bioz Verified Symbol InvivoGen is a verified supplier
Bioz Manufacturer Symbol InvivoGen manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 95

    Structured Review

    InvivoGen tlr7 8 agonist cl 075
    mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
    Tlr7 8 Agonist Cl 075, supplied by InvivoGen, used in various techniques. Bioz Stars score: 95/100, based on 209 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tlr7+8+agonist+cl+075/CL075/pmc06721845-75-12-36
    Average 95 stars, based on 209 article reviews
    tlr7 8 agonist cl 075 - by Bioz Stars, 2026-10
    95/100 stars

    Images

    1) Product Images from "TLR8 Ligation Induces Apoptosis of Monocytic Myeloid-Derived Suppressor Cells"

    Article Title: TLR8 Ligation Induces Apoptosis of Monocytic Myeloid-Derived Suppressor Cells

    Journal: Journal of leukocyte biology

    doi: 10.1002/JLB.5AB0217-070R

    mRNA expression of TLR8 (A), TLR7 (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
    Figure Legend Snippet: mRNA expression of TLR8 (A), TLR7 (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.

    Techniques Used: Expressing

    Related Articles

    Purification:

    Article Title: Modulation of dendritic cell innate and adaptive immune functions by oral and sublingual immunotherapy.
    Article Snippet: Cultures of pDCs were stimulated with media alone, 10 μg/mL of an aqueous crude cow's milk (CM) extract without preservatives (Greer Laboratories), 1.0 μg/mL of the TLR7 agonist R837 (InvivoGen, San Diego, CA) or 100 nM of the TLR9 agonist CpG ODN-2216 (TriLink, San Diego, CA). .. Cultures ofmDCs were stimulatedwith media alone, 10 μg/mL of an aqueous crude cow's milk (CM) extract without preservatives (Greer Laboratories), 10 μg/mL of the TLR2 agonist peptidoglycan from Staphylococcal aureus (Fluka Analytical, St. Louis, MO), 25 μg/mL of the TLR3 agonist polyinosinic:polycytidylic acid (poly (I:C); Sigma, St. Louis, MO), 10 ng/mL of the TLR4 agonist purified lipopolysaccharide from Escherichia coli 0111:B4 (Sigma), or 0.5 μg/mL of the TLR7/8 agonist CL-075 (InvivoGen). .. ELISA protocols for the detection of IL-6 (eBioscience, San Diego, CA), IL-10 (eBioscience), and IFN-α (in-house) from pure DC culture supernatants have been described previously [25].

    Article Title: Modulation of Dendritic Cell Innate and Adaptive Immune Functions by Oral and Sublingual Immunotherapy
    Article Snippet: Cultures of pDCs were stimulated with media alone, 10μg/mL of an aqueous crude cow's milk (CM) extract without preservatives (Greer Laboratories), 1.0μg/mL of the TLR7 agonist R837 (InvivoGen, San Diego, CA) or 100nM of the TLR9 agonist CpG ODN-2216 (TriLink, San Diego, CA). .. Cultures of mDCs were stimulated with media alone, 10μg/mL of an aqueous crude cow's milk (CM) extract without preservatives (Greer Laboratories), 10μg/mL of the TLR2 agonist peptidoglycan from Staphylococcal aureus (Fluka Analytical, St. Louis, MO), 25μg/mL of the TLR3 agonist polyinosinic:polycytidylic acid (poly (I:C); Sigma, St. Louis, MO), 10ng/mL of the TLR4 agonist purified lipopolysaccharide from Escherichia coli 0111:B4 (Sigma), or 0.5 μg/mL of the TLR7/8 agonist CL-075 (InvivoGen). .. ELISA protocols for the detection of IL-6 (eBioscience, San Diego, CA), IL-10 (eBioscience), and IFN-α (in-house) from pure DC culture supernatants have been described previously [ 25 ].

    Cell Culture:

    Article Title: TLR8 ligation induces apoptosis of monocytic myeloid-derived suppressor cells
    Article Snippet: .. PBMCs (2 × 106/ml) were cultured with 167 or 500 nM motolimod (VentiRx Pharmaceuticals, Seattle, WA, USA) or PBS for 24 h. In some assays, the cells were cultured with 0.5 μM and 2 μM of TLR7/8 agonist CL-075, 10 μMand 50 μMof TLR7 agonist Imiquimod, and 50 nM and 100 nM of TLR 9 agonist CpG ODN2006 with PBS control (all Invivogen, San Diego, CA). ..

    Article Title: TLR8 Ligation Induces Apoptosis of Monocytic Myeloid-Derived Suppressor Cells
    Article Snippet: PBMC (2×10 6 /ml) were cultured with 167nM or 500nM Motolimod (VentiRx Pharmaceuticals) or PBS for 24 hours. .. In some assays, the cells were cultured with 0.5uM and 2uM of TLR7/8 agonist CL-075, 10uM and 50uM of TLR7 agonist Imiquimod, and 50nM and 100nM of TLR 9 agonist CpG ODN2006 with PBS control (all InvivoGen). ..

    Control:

    Article Title: TLR8 ligation induces apoptosis of monocytic myeloid-derived suppressor cells
    Article Snippet: .. PBMCs (2 × 106/ml) were cultured with 167 or 500 nM motolimod (VentiRx Pharmaceuticals, Seattle, WA, USA) or PBS for 24 h. In some assays, the cells were cultured with 0.5 μM and 2 μM of TLR7/8 agonist CL-075, 10 μMand 50 μMof TLR7 agonist Imiquimod, and 50 nM and 100 nM of TLR 9 agonist CpG ODN2006 with PBS control (all Invivogen, San Diego, CA). ..

    Article Title: TLR8 Ligation Induces Apoptosis of Monocytic Myeloid-Derived Suppressor Cells
    Article Snippet: PBMC (2×10 6 /ml) were cultured with 167nM or 500nM Motolimod (VentiRx Pharmaceuticals) or PBS for 24 hours. .. In some assays, the cells were cultured with 0.5uM and 2uM of TLR7/8 agonist CL-075, 10uM and 50uM of TLR7 agonist Imiquimod, and 50nM and 100nM of TLR 9 agonist CpG ODN2006 with PBS control (all InvivoGen). ..



    Similar Products

    95
    InvivoGen tlr7 8 agonist cl 075
    mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
    Tlr7 8 Agonist Cl 075, supplied by InvivoGen, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tlr7+8+agonist+cl+075/CL075/pmc06721845-75-12-36
    Average 95 stars, based on 1 article reviews
    tlr7 8 agonist cl 075 - by Bioz Stars, 2026-10
    95/100 stars
      Buy from Supplier

    Image Search Results


    mRNA expression of TLR8 (A), TLR7 (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.

    Journal: Journal of leukocyte biology

    Article Title: TLR8 Ligation Induces Apoptosis of Monocytic Myeloid-Derived Suppressor Cells

    doi: 10.1002/JLB.5AB0217-070R

    Figure Lengend Snippet: mRNA expression of TLR8 (A), TLR7 (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.

    Article Snippet: In some assays, the cells were cultured with 0.5uM and 2uM of TLR7/8 agonist CL-075, 10uM and 50uM of TLR7 agonist Imiquimod, and 50nM and 100nM of TLR 9 agonist CpG ODN2006 with PBS control (all InvivoGen).

    Techniques: Expressing